D (continued)
- DuckTales 2
- DuckTales: Remastered
- Dungeon Explorer Sega CD
- Dynamite Cop
- Dynamite Duke
- Dynamite Headdy
- Dynowarz
- Déjà Vu
E
- Earnest Evans
- Earthworm Jim
- Earthworm Jim (SNES)
- Earthworm Jim 2 (Genesis)
- Earthworm Jim 2 (SNES)
- Edono Kiba
- Einhänder
- El Viento
- Elemental Gearbolt
- Elemental Master
- Elevator Action Returns
- Eliminate Down
- Eliminator Boat Duel
- Esper Dream
- ESWAT: City Under Siege
- Eternal Darkness - Sanity's Requiem
- Eternal Quest
- Evergrace
- ExoSquad
- Expendable
- Extermination
- Extreme-G
- Extreme-G 2
F
- F-Zero
- F-Zero X
- F1 ROC: Race of Champions
- Falsion
- Famicom Jump - Hero Retsuden
- Fantasia
- Fantasy Zone (NES)
- Fantasy Zone II
- Fatal Fury
- Fatal Fury (Genesis)
- Fatal Fury 2
- Fatal Labyrinth
- Faxanadu
- Felix the Cat
- Fester's Quest
- Fighter's History
- Fighting Force 64
- Fighting Masters
- Final Fight